RedOx Status, Proteasome and APEH: Insights into Anticancer Mechanisms of t10,c12-Conjugated Linoleic Acid Isomer on A375 Melanoma Cells

This study describes the investigation of the efficiency of conjugated linoleic acid (CLA) isomers in reducing cancer cells viability exploring the role of the oxidative stress and acylpeptide hydrolase (APEH)/proteasome mediated pathways on pro-apoptotic activity of the isomer trans10,cis12 (t10,c1...

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Bibliographic Details
Main Authors: Bergamo, Paolo, Cocca, Ennio, Palumbo, Rosanna, Gogliettino, Marta, Rossi, Mose, Palmieri, Gianna
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834215/
https://ncbi.nlm.nih.gov/pubmed/24260504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080900
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