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RedOx Status, Proteasome and APEH: Insights into Anticancer Mechanisms of t10,c12-Conjugated Linoleic Acid Isomer on A375 Melanoma Cells

This study describes the investigation of the efficiency of conjugated linoleic acid (CLA) isomers in reducing cancer cells viability exploring the role of the oxidative stress and acylpeptide hydrolase (APEH)/proteasome mediated pathways on pro-apoptotic activity of the isomer trans10,cis12 (t10,c1...

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Detalhes bibliográficos
Main Authors: Bergamo, Paolo, Cocca, Ennio, Palumbo, Rosanna, Gogliettino, Marta, Rossi, Mose, Palmieri, Gianna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834215/
https://ncbi.nlm.nih.gov/pubmed/24260504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080900
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