A MCP1 fusokine with CCR2-specific tumoricidal activity

BACKGROUND: The CCL2 chemokine is involved in promoting cancer angiogenesis, proliferation and metastasis by malignancies that express CCR2 receptor. Thus the CCL2/CCR2 axis is an attractive molecular target for anticancer drug development. METHODS: We have generated a novel fusion protein using GMC...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Rafei, Moutih, Deng, Jiusheng, Boivin, Marie-Noëlle, Williams, Patrick, Matulis, Shannon M, Yuan, Shala, Birman, Elena, Forner, Kathy, Yuan, Liangping, Castellino, Craig, Boise, Lawrence H, MacDonald, Tobey J, Galipeau, Jacques
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2011
विषय:
Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189909/
https://ncbi.nlm.nih.gov/pubmed/21943176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-121
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