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A Boundary Element Between Tsix and Xist Binds the Chromatin Insulator Ctcf and Contributes to Initiation of X-Chromosome Inactivation

In mammals, X-chromosome inactivation (XCI) equalizes X-linked gene expression between XY males and XX females and is controlled by a specialized region known as the X-inactivation center (Xic). The Xic harbors two chromatin interaction domains, one centered around the noncoding Xist gene and the ot...

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Bibliografiske detaljer
Main Authors: Spencer, Rebecca J., del Rosario, Brian C., Pinter, Stefan F., Lessing, Derek, Sadreyev, Ruslan I., Lee, Jeannie T.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189804/
https://ncbi.nlm.nih.gov/pubmed/21840866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.132662
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