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Complex regulation of the global regulatory gene csrA: CsrA-mediated translational repression, transcription from five promoters by Eσ(70) and Eσ(S), and indirect transcriptional activation by CsrA

CsrA of Escherichia coli is an RNA binding protein that globally regulates gene expression by repressing translation and/or altering the stability of target transcripts. Here we explored mechanisms that control csrA expression. Four CsrA binding sites were predicted upstream of the csrA initiation c...

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Main Authors: Yakhnin, Helen, Yakhnin, Alexander V., Baker, Carol S., Sineva, Elena, Berezin, Igor, Romeo, Tony, Babitzke, Paul
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189700/
https://ncbi.nlm.nih.gov/pubmed/21696456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2011.07723.x
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