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MafA and MafB activity in pancreatic β cells

Analyses in mouse models have revealed crucial roles for MafA and MafB in islet β cells, with MafB required during development and MafA in adults. These two closely related transcription factors regulate many genes essential for glucose sensing and insulin secretion in a cooperative and sequential m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hang, Yan, Stein, Roland
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189696/
https://ncbi.nlm.nih.gov/pubmed/21719305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2011.05.003
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