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Structural Determinants of L-type Channel Activation in Segment IIS6 Revealed by a Retinal Disorder()
The mechanism of channel opening for voltage-gated calcium channels is poorly understood. The importance of a conserved isoleucine residue in the pore-lining segment IIS6 has recently been highlighted by functional analyses of a mutation (I745T) in the Ca(V)1.4 channel causing severe visual impairme...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2005
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3189691/ https://ncbi.nlm.nih.gov/pubmed/16157588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M507013200 |
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