Rethinking the role of phosducin: Light-regulated binding of phosducin to 14-3-3 in rod inner segments

Phosducin (Pd), a small protein found abundantly in photoreceptors, is widely assumed to regulate light sensitivity in the rod outer segment through interaction with the heterotrimeric G protein transducin. But, based on histochemistry and Western blot analysis, Pd is found almost entirely in the in...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Nakano, Koichi, Chen, Jing, Tarr, George E., Yoshida, Tatsuro, Flynn, Julia M., Bitensky, Mark W.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2001
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31896/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11287646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.071067198
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