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T4 RNA ligase catalyzed synthesis of base analogue-containing oligodeoxyribonucleotides and a characterization of their thermal stabilities.

Self-complementary oligodeoxyribonucleotides containing the base analogues 2-aminopurine, 2,6-diaminopurine, N6-methyladenine, uracil, and 5-bromouracil were synthesized by a general method that allows incorporation of the analogues at specific positions. The method uses chemically synthesized parti...

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Publicat a:Nucleic Acids Res
Autors principals: Brennan, C A, Gumport, R I
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1985
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC318943/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4080551/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.24.8665
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