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Analysis of cagA in Helicobacter pylori strains from Colombian populations with contrasting gastric cancer risk reveals a biomarker for disease severity

BACKGROUND: Helicobacter pylori infection is a risk factor for the development of gastric cancer, and the bacterial oncoprotein CagA contributes to gastric carcinogenesis. METHODS: We analyzed H. pylori isolates from persons in Colombia and observed that there was marked variation among strains in l...

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Detalhes bibliográficos
Main Authors: Loh, John T., Shaffer, Carrie L., Piazuelo, M. Blanca, Bravo, Luis E., McClain, Mark S., Correa, Pelayo, Cover, Timothy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189306/
https://ncbi.nlm.nih.gov/pubmed/21859954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-11-0548
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