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Ultrasensitive detection of protein translocated through toxin pores in droplet-interface bilayers

Many bacterial toxins form proteinaceous pores that facilitate the translocation of soluble effector proteins across cellular membranes. With anthrax toxin this process may be monitored in real time by electrophysiology, where fluctuations in ionic current through these pores inserted in model membr...

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Autors principals: Fischer, Audrey, Holden, Matthew A., Pentelute, Brad L., Collier, R. John
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189069/
https://ncbi.nlm.nih.gov/pubmed/21949363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113074108
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