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Intersection of FOXO- and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression

Gene expression networks are complicated by the assortment of regulatory factors that bind DNA and modulate transcription combinatorially. Single-cell measurements can reveal biological mechanisms hidden by population averages, but their value has not been fully explored in the context of mRNA regul...

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Autors principals: Wang, Lixin, Brugge, Joan S., Janes, Kevin A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189061/
https://ncbi.nlm.nih.gov/pubmed/21873240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103423108
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