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Identifying single-cell molecular programs by stochastic profiling

Cells within tissues can be morphologically indistinguishable yet show molecular expression patterns that are remarkably heterogeneous. Here, we describe an approach for comprehensively identifying coregulated, heterogeneously expressed genes among cells that otherwise appear identical. The techniqu...

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Bibliographic Details
Main Authors: Janes, Kevin A., Wang, Chun-Chao, Holmberg, Karin J., Cabral, Kristin, Brugge, Joan S.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2849806/
https://ncbi.nlm.nih.gov/pubmed/20228812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1442
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