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Parameterizing cell-to-cell regulatory heterogeneities via stochastic transcriptional profiles

Regulated changes in gene expression underlie many biological processes, but globally profiling cell-to-cell variations in transcriptional regulation is problematic when measuring single cells. Transcriptome-wide identification of regulatory heterogeneities can be robustly achieved by randomly colle...

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Detalhes bibliográficos
Main Authors: Bajikar, Sameer S., Fuchs, Christiane, Roller, Andreas, Theis, Fabian J., Janes, Kevin A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918796/
https://ncbi.nlm.nih.gov/pubmed/24449900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311647111
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