Large common deletions associate with mortality at old age

Copy-number variants (CNVs) are a source of genetic variation that increasingly are associated with human disease. However, the role of CNVs in human lifespan is to date unknown. To identify CNVs that influence mortality at old age, we analyzed genome-wide CNV data in 5178 participants of Rotterdam...

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Hauptverfasser: Kuningas, Maris, Estrada, Karol, Hsu, Yi-Hsiang, Nandakumar, Kannabiran, Uitterlinden, André G., Lunetta, Kathryn L., van Duijn, Cornelia M., Karasik, David, Hofman, Albert, Murabito, Joanne, Rivadeneira, Fernando, Kiel, Douglas P., Tiemeier, Henning
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2011
Schlagworte:
Association Studies Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188993/
https://ncbi.nlm.nih.gov/pubmed/21835882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr340
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