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Pharmacological properties of the rhesus macaque monkey P2X7 receptor

BACKGROUND AND PURPOSE: The human P2X7 (hP2X7) receptor exhibits striking pharmacological differences from its rodent counterparts, particularly in terms of its antagonist profile. Here, we characterized the functional and pharmacological properties of the rhesus macaque monkey P2X7 (rmP2X7) recepto...

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Détails bibliographiques
Auteurs principaux: Bradley, Helen J, Browne, Liam E, Yang, Wei, Jiang, Lin-Hua
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188921/
https://ncbi.nlm.nih.gov/pubmed/21457228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01399.x
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