Role of TNF-α in virus-induced airway hyperresponsiveness and neuronal M(2) muscarinic receptor dysfunction

BACKGROUND AND PURPOSE: Infections with respiratory viruses induce exacerbations of asthma, increase acetylcholine release and potentiate vagally mediated bronchoconstriction by blocking inhibitory M(2) muscarinic receptors on parasympathetic neurons. Here we test whether virus-induced M(2) receptor...

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Detalhes bibliográficos
Main Authors: Nie, Zhenying, Scott, Gregory D, Weis, Patrick D, Itakura, Asako, Fryer, Allison D, Jacoby, David B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188913/
https://ncbi.nlm.nih.gov/pubmed/21457223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01393.x
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