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Etanercept prevents airway hyperresponsiveness by protecting neuronal M(2) muscarinic receptors in antigen-challenged guinea pigs
BACKGROUND AND PURPOSE: Increased tumour necrosis factor-α (TNF-α) is associated with airway hyperreactivity in antigen-challenged animals. In human asthmatics, TNF-α is increased and blocking it prevents airway hyperreactivity in some asthmatic patients. However, the mechanisms by which TNF-α media...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2697771/ https://ncbi.nlm.nih.gov/pubmed/19134001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00045.x |
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