N-WASp is required for Schwann cell cytoskeletal dynamics, normal myelin gene expression and peripheral nerve myelination

Schwann cells elaborate myelin sheaths around axons by spirally wrapping and compacting their plasma membranes. Although actin remodeling plays a crucial role in this process, the effectors that modulate the Schwann cell cytoskeleton are poorly defined. Here, we show that the actin cytoskeletal regu...

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Bibliographische Detailangaben
Hauptverfasser: Jin, Fuzi, Dong, Baoxia, Georgiou, John, Jiang, Qiuhong, Zhang, Jinyi, Bharioke, Arjun, Qiu, Frank, Lommel, Silvia, Feltri, M. Laura, Wrabetz, Lawrence, Roder, John C., Eyer, Joel, Chen, Xiequn, Peterson, Alan C., Siminovitch, Katherine A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2011
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188810/
https://ncbi.nlm.nih.gov/pubmed/21385763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.058677
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