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A statistical framework for modeling gene expression using chromatin features and application to modENCODE datasets

We develop a statistical framework to study the relationship between chromatin features and gene expression. This can be used to predict gene expression of protein coding genes, as well as microRNAs. We demonstrate the prediction in a variety of contexts, focusing particularly on the modENCODE worm...

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Detalhes bibliográficos
Main Authors: Cheng, Chao, Yan, Koon-Kiu, Yip, Kevin Y, Rozowsky, Joel, Alexander, Roger, Shou, Chong, Gerstein, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188797/
https://ncbi.nlm.nih.gov/pubmed/21324173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-2-r15
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