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Age-dependent Dystrophin Loss and Genetic Reconstitution Establish a Molecular Link Between Dystrophin and Heart Performance During Aging

The aging-related decline in cardiac function is an important public health problem. The molecular basis of age-dependent loss of cardiac function is largely unknown and there are no effective therapies addressing this important form of heart disease. This study evaluates the role of the cytoskeleta...

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Detalhes bibliográficos
Main Authors: Townsend, DeWayne, Daly, Michael, Chamberlain, Jeffrey S, Metzger, Joseph M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188736/
https://ncbi.nlm.nih.gov/pubmed/21730971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.120
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