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Mesothelial- and epithelial-derived FGF9 have distinct functions in the regulation of lung development

Fibroblast growth factor (FGF) 9 is a secreted signaling molecule that is expressed in lung mesothelium and epithelium and is required for lung development. Embryos lacking FGF9 show mesenchymal hypoplasia, decreased epithelial branching and, by the end of gestation, hypoplastic lungs that cannot su...

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Hlavní autoři: Yin, Yongjun, Wang, Fen, Ornitz, David M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188607/
https://ncbi.nlm.nih.gov/pubmed/21750028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.065110
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