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Mesothelial- and epithelial-derived FGF9 have distinct functions in the regulation of lung development

Fibroblast growth factor (FGF) 9 is a secreted signaling molecule that is expressed in lung mesothelium and epithelium and is required for lung development. Embryos lacking FGF9 show mesenchymal hypoplasia, decreased epithelial branching and, by the end of gestation, hypoplastic lungs that cannot su...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yin, Yongjun, Wang, Fen, Ornitz, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188607/
https://ncbi.nlm.nih.gov/pubmed/21750028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.065110
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