Mucin Variable Number Tandem Repeat Polymorphisms and Severity of Cystic Fibrosis Lung Disease: Significant Association with MUC5AC

Variability in cystic fibrosis (CF) lung disease is partially due to non-CFTR genetic modifiers. Mucin genes are very polymorphic, and mucins play a key role in the pathogenesis of CF lung disease; therefore, mucin genes are strong candidates as genetic modifiers. DNA from CF patients recruited for...

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Autors principals: Guo, XueLiang, Pace, Rhonda G., Stonebraker, Jaclyn R., Commander, Clayton W., Dang, Anthony T., Drumm, Mitchell L., Harris, Ann, Zou, Fei, Swallow, Dallas M., Wright, Fred A., O'Neal, Wanda K., Knowles, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188583/
https://ncbi.nlm.nih.gov/pubmed/21998660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025452
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