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Polymer support oligonucleotide synthesis XVIII: use of beta-cyanoethyl-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product.

Various 5'O-N-protected deoxynucleoside-3'-O-beta-cyanoethyl-N,N-dialkylamino-/N- morpholinophosphoramidites were prepared from beta-cyanoethyl monochlorophosphoramidites of N,N-dimethylamine, N,N-diisopropylamine and N-morpholine. These active deoxynucleoside phosphates have successfully...

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Main Authors: Sinha, N D, Biernat, J, McManus, J, Köster, H
Formato: Artigo
Idioma:Inglês
Publicado: 1984
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC318857/
https://ncbi.nlm.nih.gov/pubmed/6547529
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