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Gene Knockdowns in Adult Animals: PPMOs and Vivo-Morpholinos

Antisense molecules do not readily cross cell membranes. This has limited the use of antisense to systems where techniques have been worked out to introduce the molecules into cells, such as embryos and cell cultures. Uncharged antisense bearing a group of guanidinium moieties on either a linear pep...

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书目详细资料
Principais autores: Shan Jiang, Jon D. Moulton
格式: Artigo
语言:Inglês
出版: MDPI AG 2009-03-01
丛编:Molecules
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在线阅读:http://www.mdpi.com/1420-3049/14/3/1304/
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