Influence of ROBO1 and RORA on Risk of Age-Related Macular Degeneration Reveals Genetically Distinct Phenotypes in Disease Pathophysiology

ROBO1 is a strong candidate gene for age-related macular degeneration (AMD) based upon its location under a linkage peak on chromosome 3p12, its expression pattern, and its purported function in a pathway that includes RORA, a gene previously associated with risk for neovascular AMD. Previously, we...

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Main Authors: Jun, Gyungah, Nicolaou, Michael, Morrison, Margaux A., Buros, Jacqueline, Morgan, Denise J., Radeke, Monte J., Yonekawa, Yoshihiro, Tsironi, Evangelia E., Kotoula, Maria G., Zacharaki, Fani, Mollema, Nissa, Yuan, Yang, Miller, Joan W., Haider, Neena B., Hageman, Gregory S., Kim, Ivana K., Schaumberg, Debra A., Farrer, Lindsay A., DeAngelis, Margaret M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188561/
https://ncbi.nlm.nih.gov/pubmed/21998696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025775
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