Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: A systems biology based approach

To identify novel genes and pathways associated with AMD, we performed microarray gene expression and linkage analysis which implicated the candidate gene, retinoic acid receptor-related orphan receptor alpha (RORA, 15q). Subsequent genotyping of 159 RORA single nucleotide polymorphisms (SNPs) in a...

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Detalhes bibliográficos
Principais autores: Silveira, Alexandra C., Morrison, Margaux A., Ji, Fei, Xu, Haiyan, Reinecke, James B., Adams, Scott M., Arneberg, Trevor M., Janssian, Maria, Lee, Joo-Eun, Yuan, Yang, Schaumberg, Debra A., Kotoula, Maria G., Tsironi, Evangeline E., Tsiloulis, Aristoteles N., Chatzoulis, Dimitrios Z., Miller, Joan W., Kim, Ivana K., Hageman, Gregory H., Farrer, Lindsay A., Haider, Neena B., DeAngelis, Margaret M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884392/
https://ncbi.nlm.nih.gov/pubmed/19786043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.visres.2009.09.016
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