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Dynamic Replacement of Histone H3 Variants Reprograms Epigenetic Marks in Early Mouse Embryos

Upon fertilization, reprogramming of gene expression is required for embryo development. This step is marked by DNA demethylation and changes in histone variant composition. However, little is known about the molecular mechanisms causing these changes and their impact on histone modifications. We ex...

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Hlavní autoři: Akiyama, Tomohiko, Suzuki, Osamu, Matsuda, Junichiro, Aoki, Fugaku
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188537/
https://ncbi.nlm.nih.gov/pubmed/21998593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002279
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