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Hydrophobicity and Charge Shape Cellular Metabolite Concentrations

What governs the concentrations of metabolites within living cells? Beyond specific metabolic and enzymatic considerations, are there global trends that affect their values? We hypothesize that the physico-chemical properties of metabolites considerably affect their in-vivo concentrations. The recen...

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Detalhes bibliográficos
Main Authors: Bar-Even, Arren, Noor, Elad, Flamholz, Avi, Buescher, Joerg M., Milo, Ron
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188480/
https://ncbi.nlm.nih.gov/pubmed/21998563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002166
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