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Increased O-linked β-N-acetylglucosamine levels on proteins improves survival, reduces inflammation and organ damage 24 hours after trauma-hemorrhage in rats

OBJECTIVE: We have previously shown that increasing protein O-linked β-N-acetylglucosamine (O-GlcNAc) levels by different mechanisms reduced inflammatory responses and improved organ function 2 hours after trauma-hemorrhage (T-H). The aim of the study was to evaluate the effects of O-GlcNAc levels o...

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Autors principals: Nöt, Laszlo G, Brocks, Charlye A, Vámhidy, Laszlo, Marchase, Richard B, Chatham, John C
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188403/
https://ncbi.nlm.nih.gov/pubmed/20016375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e3181cb10b3
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