Human Glial-Restricted Progenitor Transplantation into Cervical Spinal Cord of the SOD1(G93A) Mouse Model of ALS

Cellular abnormalities are not limited to motor neurons in amyotrophic lateral sclerosis (ALS). There are numerous observations of astrocyte dysfunction in both humans with ALS and in SOD1(G93A) rodents, a widely studied ALS model. The present study therapeutically targeted astrocyte replacement in...

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Main Authors: Lepore, Angelo C., O'Donnell, John, Kim, Andrew S., Williams, Timothy, Tuteja, Alicia, Rao, Mahendra S., Kelley, Linda L., Campanelli, James T., Maragakis, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187829/
https://ncbi.nlm.nih.gov/pubmed/21998733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025968
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