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Human Glial-Restricted Progenitor Transplantation into Cervical Spinal Cord of the SOD1(G93A) Mouse Model of ALS

Cellular abnormalities are not limited to motor neurons in amyotrophic lateral sclerosis (ALS). There are numerous observations of astrocyte dysfunction in both humans with ALS and in SOD1(G93A) rodents, a widely studied ALS model. The present study therapeutically targeted astrocyte replacement in...

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Detalhes bibliográficos
Main Authors: Lepore, Angelo C., O'Donnell, John, Kim, Andrew S., Williams, Timothy, Tuteja, Alicia, Rao, Mahendra S., Kelley, Linda L., Campanelli, James T., Maragakis, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187829/
https://ncbi.nlm.nih.gov/pubmed/21998733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025968
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