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Stress-responsive maturation of Clk1/4 pre-mRNAs promotes phosphorylation of SR splicing factor

It has been assumed that premessenger ribonucleic acids (RNAs; pre-mRNAs) are spliced cotranscriptionally in the process of gene expression. However, in this paper, we report that splicing of Clk1/4 mRNAs is suspended in tissues and cultured cells and that intermediate forms retaining specific intro...

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Autors principals: Ninomiya, Kensuke, Kataoka, Naoyuki, Hagiwara, Masatoshi
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187705/
https://ncbi.nlm.nih.gov/pubmed/21949414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201107093
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