Primary Infection by a Human Immunodeficiency Virus with Atypical Coreceptor Tropism

The great majority of human immunodeficiency virus type 1 (HIV-1) strains enter CD4(+) target cells by interacting with one of two coreceptors, CCR5 or CXCR4. Here we describe a transmitted/founder (T/F) virus (ZP6248) that was profoundly impaired in its ability to utilize CCR5 and CXCR4 coreceptors...

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主要な著者: Jiang, Chunlai, Parrish, Nicholas F., Wilen, Craig B., Li, Hui, Chen, Yue, Pavlicek, Jeffrey W., Berg, Anna, Lu, Xiaozhi, Song, Hongshuo, Tilton, John C., Pfaff, Jennifer M., Henning, Elizabeth A., Decker, Julie M., Moody, M. Anthony, Drinker, Mark S., Schutte, Robert, Freel, Stephanie, Tomaras, Georgia D., Nedellec, Rebecca, Mosier, Donald E., Haynes, Barton F., Shaw, George M., Hahn, Beatrice H., Doms, Robert W., Gao, Feng
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2011
主題:
Genetic Diversity and Evolution
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187499/
https://ncbi.nlm.nih.gov/pubmed/21835785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05249-11
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