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Primary Infection by a Human Immunodeficiency Virus with Atypical Coreceptor Tropism

The great majority of human immunodeficiency virus type 1 (HIV-1) strains enter CD4(+) target cells by interacting with one of two coreceptors, CCR5 or CXCR4. Here we describe a transmitted/founder (T/F) virus (ZP6248) that was profoundly impaired in its ability to utilize CCR5 and CXCR4 coreceptors...

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Detalhes bibliográficos
Main Authors: Jiang, Chunlai, Parrish, Nicholas F., Wilen, Craig B., Li, Hui, Chen, Yue, Pavlicek, Jeffrey W., Berg, Anna, Lu, Xiaozhi, Song, Hongshuo, Tilton, John C., Pfaff, Jennifer M., Henning, Elizabeth A., Decker, Julie M., Moody, M. Anthony, Drinker, Mark S., Schutte, Robert, Freel, Stephanie, Tomaras, Georgia D., Nedellec, Rebecca, Mosier, Donald E., Haynes, Barton F., Shaw, George M., Hahn, Beatrice H., Doms, Robert W., Gao, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187499/
https://ncbi.nlm.nih.gov/pubmed/21835785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05249-11
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