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Characterization of Escherichia coli UmuC Active-Site Loops Identifies Variants That Confer UV Hypersensitivity

DNA is constantly exposed to chemical and environmental mutagens, causing lesions that can stall replication. In order to deal with DNA damage and other stresses, Escherichia coli utilizes the SOS response, which regulates the expression of at least 57 genes, including umuDC. The gene products of um...

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Bibliografski detalji
Glavni autori: Hawver, Lisa A., Gillooly, Caitlin A., Beuning, Penny J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187380/
https://ncbi.nlm.nih.gov/pubmed/21784925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.05301-11
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