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Characterization of Escherichia coli UmuC Active-Site Loops Identifies Variants That Confer UV Hypersensitivity

DNA is constantly exposed to chemical and environmental mutagens, causing lesions that can stall replication. In order to deal with DNA damage and other stresses, Escherichia coli utilizes the SOS response, which regulates the expression of at least 57 genes, including umuDC. The gene products of um...

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Detaylı Bibliyografya
Asıl Yazarlar: Hawver, Lisa A., Gillooly, Caitlin A., Beuning, Penny J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187380/
https://ncbi.nlm.nih.gov/pubmed/21784925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.05301-11
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