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Comparative Genomics of esx Genes from Clinical Isolates of Mycobacterium tuberculosis Provides Evidence for Gene Conversion and Epitope Variation

The 23-membered Esx protein family is involved in the host-pathogen interactions of Mycobacterium tuberculosis. These secreted proteins are among the most immunodominant antigens recognized by the human immune system and have thus been used to develop vaccines and immunodiagnostic tests for tubercul...

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Detalhes bibliográficos
Main Authors: Uplekar, Swapna, Heym, Beate, Friocourt, Véronique, Rougemont, Jacques, Cole, Stewart T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187259/
https://ncbi.nlm.nih.gov/pubmed/21807910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05344-11
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