Pneumolysin with Low Hemolytic Activity Confers an Early Growth Advantage to Streptococcus pneumoniae in the Blood

Streptococcus pneumoniae is a leading cause of human diseases such as pneumonia, bacteremia, meningitis, and otitis media. Pneumolysin (Ply) is an important virulence factor of S. pneumoniae and a promising future vaccine target. However, the expansion of clones carrying ply alleles with reduced hem...

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Main Authors: Harvey, Richard M., Ogunniyi, Abiodun D., Chen, Austen Y., Paton, James C.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2011
主題:
Bacterial Infections
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187248/
https://ncbi.nlm.nih.gov/pubmed/21788389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05418-11
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