Targeted Disruption of Nonribosomal Peptide Synthetase pes3 Augments the Virulence of Aspergillus fumigatus

Nonribosomal peptide synthesis (NRPS) is a documented virulence factor for the opportunistic pathogen Aspergillus fumigatus and other fungi. Secreted or intracellularly located NRP products include the toxic molecule gliotoxin and the iron-chelating siderophores triacetylfusarinine C and ferricrocin...

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Autores principales: O'Hanlon, Karen A., Cairns, Timothy, Stack, Deirdre, Schrettl, Markus, Bignell, Elaine M., Kavanagh, Kevin, Miggin, Sinéad M., O'Keeffe, Grainne, Larsen, Thomas O., Doyle, Sean
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2011
Materias:
Fungal and Parasitic Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187245/
https://ncbi.nlm.nih.gov/pubmed/21746855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00192-11
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