Interferon Regulatory Transcription Factor 3 Protects Mice from Uterine Horn Pathology during Chlamydia muridarum Genital Infection

Mice with the type I interferon (IFN) receptor gene knocked out (IFNAR KO mice) or deficient for alpha/beta IFN (IFN-α/β) signaling clear chlamydial infection earlier than control mice and develop less oviduct pathology. Initiation of host IFN-β transcription during an in vitro chlamydial infection...

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Detalhes bibliográficos
Main Authors: Prantner, Daniel, Sikes, James D., Hennings, Leah, Savenka, Alena V., Basnakian, Alexei G., Nagarajan, Uma M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187243/
https://ncbi.nlm.nih.gov/pubmed/21788382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00140-11
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