Critical Role for Interleukin-1β (IL-1β) during Chlamydia muridarum Genital Infection and Bacterial Replication-Independent Secretion of IL-1β in Mouse Macrophages

Recent findings have implicated interleukin-1β (IL-1β) as an important mediator of the inflammatory response in the female genital tract during chlamydial infection. But how IL-1β is produced and its specific role in infection and pathology are unclear. Therefore, our goal was to determine the funct...

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Detalhes bibliográficos
Main Authors: Prantner, Daniel, Darville, Toni, Sikes, James D., Andrews, Charles W., Brade, Helmut, Rank, Roger G., Nagarajan, Uma M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786476/
https://ncbi.nlm.nih.gov/pubmed/19805535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00883-09
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