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Mutagenic Analysis of the Clostridium difficile Flagellar Proteins, FliC and FliD, and Their Contribution to Virulence in Hamsters

Although toxins A and B are known to be important contributors to the acute phase of Clostridium difficile infection, the role of colonization and adherence to host tissues in the overall pathogenesis of these organisms remains unclear. Consequently, we used the recently introduced intron-based Clos...

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Bibliographic Details
Main Authors: Dingle, Tanis C., Mulvey, George L., Armstrong, Glen D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187235/
https://ncbi.nlm.nih.gov/pubmed/21788384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05305-11
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