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Mutagenic Analysis of the Clostridium difficile Flagellar Proteins, FliC and FliD, and Their Contribution to Virulence in Hamsters

Although toxins A and B are known to be important contributors to the acute phase of Clostridium difficile infection, the role of colonization and adherence to host tissues in the overall pathogenesis of these organisms remains unclear. Consequently, we used the recently introduced intron-based Clos...

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Bibliografske podrobnosti
Main Authors: Dingle, Tanis C., Mulvey, George L., Armstrong, Glen D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187235/
https://ncbi.nlm.nih.gov/pubmed/21788384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05305-11
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