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The Insect Peptide Coprisin Prevents Clostridium difficile-Mediated Acute Inflammation and Mucosal Damage through Selective Antimicrobial Activity

Clostridium difficile-associated diarrhea and pseudomembranous colitis are typically treated with vancomycin or metronidazole, but recent increases in relapse incidence and the emergence of drug-resistant strains of C. difficile indicate the need for new antibiotics. We previously isolated coprisin,...

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Autori principali: Kang, Jin Ku, Hwang, Jae Sam, Nam, Hyo Jung, Ahn, Keun Jae, Seok, Heon, Kim, Sung-Kuk, Yun, Eun Young, Pothoulakis, Charalabos, Lamont, John Thomas, Kim, Ho
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186999/
https://ncbi.nlm.nih.gov/pubmed/21807975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00177-11
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