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gp96 Is a Human Colonocyte Plasma Membrane Binding Protein for Clostridium difficile Toxin A
Clostridium difficile toxin A (TxA), a key mediator of antibiotic-associated colitis, requires binding to a cell surface receptor prior to internalization. Our aim was to identify novel plasma membrane TxA binding proteins on human colonocytes. TxA was coupled with biotin and cross-linked to the sur...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology (ASM)
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2446715/ https://ncbi.nlm.nih.gov/pubmed/18411291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00326-08 |
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