gp96 Is a Human Colonocyte Plasma Membrane Binding Protein for Clostridium difficile Toxin A

Clostridium difficile toxin A (TxA), a key mediator of antibiotic-associated colitis, requires binding to a cell surface receptor prior to internalization. Our aim was to identify novel plasma membrane TxA binding proteins on human colonocytes. TxA was coupled with biotin and cross-linked to the sur...

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Detaylı Bibliyografya
Asıl Yazarlar: Na, Xi, Kim, Ho, Moyer, Mary P., Pothoulakis, Charalabos, LaMont, J. Thomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Molecular Pathogenesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446715/
https://ncbi.nlm.nih.gov/pubmed/18411291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00326-08
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