Resistance to Cancer Treatment: The Role of Somatic Genetic Events and the Challenges for Targeted Therapies

Therapeutic resistance remains a major cause of cancer-related deaths. Resistance can occur from the outset of treatment or as an acquired phenomenon after an initial clinical response. Therapeutic resistance is an almost universal phenomenon in the treatment of metastatic cancers. The advent of mol...

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Detalhes bibliográficos
Main Authors: Batist, Gerald, Wu, Jian Hui, Spatz, Alan, Miller, Wilson H., Cocolakis, Eftihia, Rousseau, Caroline, Diaz, Zuanel, Ferrario, Cristiano, Basik, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186943/
https://ncbi.nlm.nih.gov/pubmed/22007174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2011.00059
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