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Modulation of GSK-3 as a Therapeutic Strategy on Tau Pathologies

Glycogen synthase kinase-3 (GSK-3) is ubiquitously expressed and unusually active in resting, non-stimulated cells. In mammals, at least three proteins (α, β1, and β2), generated from two different genes, gsk-3α and gsk-3β, are widely expressed at both the RNA and protein levels although some tissue...

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Hlavní autoři: Medina, Miguel, Garrido, Juan Jose, Wandosell, Francisco G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Research Foundation 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186940/
https://ncbi.nlm.nih.gov/pubmed/22007157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2011.00024
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