Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions

Malignant gliomas contain a population of self-renewing tumorigenic stem-like cells; however, it remains unclear how these glioma stem cells (GSCs) self-renew or generate cellular diversity at the single-cell level. Asymmetric cell division is a proposed mechanism to maintain cancer stem cells, yet...

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Autors principals: Lathia, J D, Hitomi, M, Gallagher, J, Gadani, S P, Adkins, J, Vasanji, A, Liu, L, Eyler, C E, Heddleston, J M, Wu, Q, Minhas, S, Soeda, A, Hoeppner, D J, Ravin, R, McKay, R D G, McLendon, R E, Corbeil, D, Chenn, A, Hjelmeland, A B, Park, D M, Rich, J N
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186899/
https://ncbi.nlm.nih.gov/pubmed/21881602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.80
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