Targeting ALDH(bright) human carcinoma initiating cells with ALDH1A1- specific CD8(+) T cells

PURPOSE: Tumor cells expressing elevated aldehyde dehydrogenase (ALDH) activity attributed to ALDH1/3 isoforms have been identified as ALDH(bright) cells and have the properties attributed to cancer initiating cells (CIC). CIC represent the subpopulation of tumor cells that are resistant to conventi...

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Detalhes bibliográficos
Main Authors: Visus, Carmen, Wang, Yangyang, Lozano-Leon, Antonio, Ferris, Robert L., Silver, Susan, Szczepanski, Miroslaw J., Brand, Randall E., Ferrone, Cristina R., Whiteside, Theresa L., Ferrone, Soldano, DeLeo, Albert B., Wang, Xinhui
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186874/
https://ncbi.nlm.nih.gov/pubmed/21856769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-1111
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